Cardiac autophagy is a maladaptive response to hemodynamic stress
J. Clin. Invest. Hongxin Zhu, et al. 117:1782 doi:10.1172/JCI27523 [Go to this article.]

Figure 2
Increased abundance of lysosomal markers in sTAB ventricle. LAMP-1 (A) and cathepsin D (B), detected by immunohistochemistry, are increased in sTAB ventricle at multiple time points, indicative of increased lysosomal activity in pressure-stressed LVs. Scale bars: 40 μm. (C) Representative immunoblot of ventricular lysates from sham-operated and sTAB LVs probed for cathepsin D. Mean data from 3 independent experiments. *P < 0.05.