Role of A2B
adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
J. Clin. Invest. Chun-Xiao Sun, et al. 116:2173 doi:10.1172/JCI27303 [
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Figure 6CVT-6883 treatment inhibits the expression of genes associated with alveolar airway destruction. Transcript levels of TIMP-1 (
A), MMP-9 (
B), and MMP-12 (
C) were measured in whole-lung RNA extracts from postnatal day 38 mice using quantitative RT-PCR. Data are mean pg transcript/μg RNA ± SEM. *
P ≤ 0.05 versus vehicle-treated
ADA+ mice;
#P ≤ 0.05 versus vehicle-treated
ADA–/– mice.
n = 4 (
ADA+), 8 (
ADA–/–).
