Role of A2B
adenosine receptor signaling in adenosine-dependent pulmonary inflammation and injury
J. Clin. Invest. Chun-Xiao Sun, et al. 116:2173 doi:10.1172/JCI27303 [
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Figure 4Production of proinflammatory cytokines. Transcript levels of various proinflammatory cytokines were measured in whole-lung extracts from postnatal day 38 mice using quantitative RT-PCR. Shown are levels of (
A) TNF-α, (
B) IL-6, (
C) CXCL2, (
D) CCL11, (
E) CCL17, and (
F) CXCL1. Results are presented as mean pg transcript/μg RNA ± SEM. *
P ≤ 0.05 versus vehicle-treated
ADA+ mice;
#P ≤ 0.05 versus vehicle-treated
ADA–/– mice.
n = 4 (
ADA+), 8 (
ADA–/–). ND, not detected.
