Met-regulated expression signature defines a subset of human hepatocellular carcinomas with poor prognosis and aggressive phenotype
J. Clin. Invest. Pal Kaposi-Novak, et al. 116:1582 doi:10.1172/JCI27236 [Go to this article.]

Figure 1
Diagram of data analysis. HGF/Met–regulated genes were identified by comparison of expression profiles from WT and Met KO hepatocytes. Expression of common orthologous HGF target genes was also assessed in 2 independent HCC data sets. The classifier was constructed from cross-species–conserved HGF/Met target genes to predict patient survival. Results were validated with multiple prediction algorithms on separate training and validation sets of HCC samples. FDR, false discovery rate.