Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance
J. Clin. Invest. Stephanie Dillon, et al. 116:916 doi:10.1172/JCI27203 [
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Figure 4IL-10 regulates the induction of TNF-α, IL-12, and IL-6 in DCs. Wild-type or IL-10–deficient murine splenic DCs were cultured with zymosan (100 μg/ml) and CD40 ligand cells for 24 hours, and levels of cytokines were assayed by ELISA.