HTLV-1 propels untransformed CD4+
lymphocytes into the cell cycle while protecting CD8+
cells from death
J. Clin. Invest. David Sibon, et al. 116:974 doi:10.1172/JCI27198 [
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Figure 5
HTLV-1 recruits untransformed CD4
+
lymphocytes into the cell cycle while preventing CD8
+
cells from cell death.
CD4
+ and CD8
+ clones (66 clones) were analyzed at day 6 from PHA stimulation for cell cycle (
A and
B) and apoptosis (
A and
C).
#P = 0.001,
##P = 0.04 versus uninfected cells of the same phenote.