HTLV-1 propels untransformed CD4+
lymphocytes into the cell cycle while protecting CD8+
cells from death
J. Clin. Invest. David Sibon, et al. 116:974 doi:10.1172/JCI27198 [
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Figure 4
Altered growth kinetics of CD4
+
and CD8
+
HTLV-1–infected clones.
Sixty-six clones were analyzed. (
A) Increased growth of HTLV-1–infected clones. (
B) Increased growth of CD4
+ and CD8
+ HTLV-1–infected clones. (
C) Kinetics of IL-2–dependent clonal proliferation of infected and uninfected clones. (
D) Kinetics of IL-2–dependent clonal proliferation of infected and uninfected CD4
+ and CD8
+ clones. (
E) Spontaneous clonal proliferation of infected and uninfected CD4
+ and CD8
+ clones.