Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation
J. Clin. Invest. Athanasios Stratis, et al. 116:2094 doi:10.1172/JCI27179 [
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Figure 7
Elimination of granulocytes from the skin of K14-Cre-IKK2
fl/fl
mice does not suppress inflammation.
Confocal images of frozen skin sections from CD18
–/– K14-Cre-IKK2
fl/fl mice (left panels) and CD18
+/– K14-Cre-IKK2
fl/fl mice (right panels) immunostained for the indicated immune cell markers and phosphorylated STAT3 (green). Nuclei are stained red. White dotted lines indicate the position of the epidermal basement membrane. Scale bar: 40 μm.