Insulin’s direct effects on the liver dominate the control of hepatic glucose production
J. Clin. Invest. Dale S. Edgerton, et al. 116:521 doi:10.1172/JCI27073 [Go to this article.]

Figure 7
Percentage of hepatic sinusoidal glucagon and arterial plasma FFA and glucose with respect to basal levels during the last 2 hours in 18-hour-fasted conscious dogs. Basal insulin infusion was switched from the portal vein either to a peripheral vein (white bars) or to head arteries (black bars) between 0 and 180 minutes. Mean ± SEM.