CFTR is required for PKA-regulated ATP sensitivity of Kir1.1 potassium channels in mouse kidney
J. Clin. Invest. Ming Lu, et al. 116:797 doi:10.1172/JCI26961 [
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Figure 4Low concentration of cytosolic Mg-ATP stimulated ROMK channels in inside-out patches from TAL apical membrane. Representative continuing recordings show low intracellular Mg-ATP (100–500 μM) reactivated ROMK channels following rundown in both wild-type (
A) and mCFTR
–/– mice (
B).