Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia
J. Clin. Invest. Tanya Tolmachova, et al. 116:386 doi:10.1172/JCI26617 [Go to this article.]

Figure 5
Electron microscopic analysis of Chm mutant retinas. (A–D) Different sections from the eye of a 9-month-old Chm^null/WT female mouse. (E) A TM-induced Chm^3lox/Y MerCreMer mouse. (F) A Chm^flox/Y six3-Cre mouse. (G) A Chm^WT/Y six3-Cre mouse. RPE nuclei are marked by asterisks. Abnormal cells above the RPE are shown by arrowheads in C and E. Nuclei of cells from the ONL are marked by arrows in D and F. Scale bars: 2 μm (A–E) or 7 μm (F and G).