Disease-associated mutations affect intracellular traffic and paracellular Mg2+ transport function of Claudin-16
J. Clin. Invest. P. Jaya Kausalya, et al. 116:878 doi:10.1172/JCI26323 [
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Figure 3Cell surface expression of Cldn16 mutants linked to FHHNC. HeLa cells transiently expressing the indicated HA-tagged Cldn16 mutants were incubated in the presence of anti-loop antibody for 1 hour at 37°C and then immunostained to detect the HA tag (red) or the anti-loop antibody (green). Merged images are shown. Shown are representative images of 2–3 independent experiments.
