CD4+ T cell–independent DNA vaccination against opportunistic infections
J. Clin. Invest. Mingquan Zheng, et al. 115:3536 doi:10.1172/JCI26306 [
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Figure 6Protection against a primary PC challenge in CD4-depleted mice after DNA immunization. CD4-depleted mice were vaccinated with 3 rounds of control (pCD40L), pKexin, or pKexin/CD40L followed by challenge with PC. PC was quantified by quantitative real-time PCR (
A) or by histology (
B).
n = 4–6. All data are mean values ± SEM. *
P < 0.05, **
P < 0.01 compared with control.