CD4+ T cell–independent DNA vaccination against opportunistic infections
J. Clin. Invest. Mingquan Zheng, et al. 115:3536 doi:10.1172/JCI26306 [
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Figure 2Anti-OVA IgG1 (
A) and IgG2a (
B) responses after AdOVA or AdOVA/CD40L boosting after intramuscular DNA priming with pOVA or pOVA/CD40L in CD4-depleted and CD4-replete mice.
n = 6–8 per group All data are mean titer ± SEM. *
P < 0.05 compared with control; **
P < 0.01 compared with control. A line denotes the limit of detection in the ELISA.