Decreased vascular lesion formation in mice with inducible endothelial-specific expression of protein kinase Akt
J. Clin. Invest. Yasushi Mukai, et al. 116:334 doi:10.1172/JCI26223 [Go to this article.]

Figure 9
Vascular inflammation following carotid artery ligation. (A) Immunostaining of the vascular wall for leukocyte accumulation (CD45-positive cells), the expression of ICAM-1 and VCAM-1, and cellular proliferation in sham-operated, WT, and induced EC-Akt Tg mice after carotid artery ligation. Arrows indicate positively stained cells. Scale bar: 50 μm. (B) Quantification of cells that stained positively for CD45 antigen or PCNA. Results are expressed as mean ± SEM. n = 4 in each group. *P < 0.05 versus WT.