Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL
J. Clin. Invest. Tomas Vaisar, et al. 117:746 doi:10.1172/JCI26206 [
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Figure 4Peptide number and number of subjects with detectable peptides in HDL
3 isolated from control subjects and CAD subjects.
HDL
3 was isolated from the plasma of 6 control subjects and 7 subjects with established CAD (group 2; Table
1). HDL-associated proteins were subjected to LC-ESI-MS/MS analysis. All protein identifications required detection of at least 2 unique peptides from each protein from at least 2 individuals (Table
1). The
P value was assessed by Student’s
t test (peptide number) or Fisher’s exact test (subject number). *
P < 0.05.