The H1 histamine receptor regulates allergic lung responses
J. Clin. Invest. Paul J. Bryce, et al. 116:1624 doi:10.1172/JCI26150 [Go to this article.]

Figure 5
Inflammatory airway responses to antigen can be induced by WT T cells but not by H1R^–/– T cells. Antigen-expanded CD4⁺ T cells from WT or H1R^–/– mice were adoptively transferred into naive WT or H1R^–/– recipients, and the development of airway inflammation was studied after inhaled OVA challenge. (A) The numbers of eosinophils, neutrophils, and lymphocytes in BAL fluid were determined (n = 9/group). **P < 0.01, Student’s t test. (B) Representative lung histology at ×200 magnification. Sections were stained with H&E.