Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes
J. Clin. Invest. Aimee M. Powelka, et al. 116:125 doi:10.1172/JCI26040 [
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Figure 5RIP140 reexpression in RIPKO-1 adipocytes results in downregulation of multiple metabolic pathways. Ten days after the induction of differentiation, RNA was isolated from RIPKO-1 adipocytes and RIPKO-1 adipocytes stably expressing RIP140 using a lentiviral vector and used for Affymetrix GeneChip analysis. The number of genes in the indicated metabolic pathways that were significantly (
P < 0.05) upregulated, downregulated, or not changed is shown from left to right in the graphs.