Shigatoxin triggers thrombotic thrombocytopenic purpura in genetically susceptible ADAMTS13-deficient mice
J. Clin. Invest. David G. Motto, et al. 115:2752 doi:10.1172/JCI26007 [Go to this article.]

Figure 2
Kaplan-Meier survival plot for ADAMTS13-deficient mice and littermate controls. (A) Adamts13^B/129+/+, Adamts13^B/129+/–, and Adamts13^B/129–/– mice (n = 579 mice). (B) Adamts13^B/CN1+/+, Adamts13^B/CN1+/–, and Adamts13^B/CN1–/– mice (n = 658 mice). (C) Adamts13^B/CN2+/+, Adamts13^B/CN2+/–, and Adamts13^B/CN2–/– mice (n = 169 mice). Probability of survival was calculated and plotted using the R Statistical Computing Package (39).