Sodium channel mutations in epilepsy
and other neurological disorders
J. Clin. Invest. Miriam H. Meisler, et al. 115:2010 doi:10.1172/JCI25466 [
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Figure 1The sodium channel α and β subunits are transmembrane proteins. The 4 homologous domains of the α subunit are represented in different colors. The transmembrane segments associate in the membrane to form an Na
+-permeable pore lined by the re-entrant S5–S6 pore-loop segments (inset).