Epimorphin^–/– mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis
J. Clin. Invest. Yuan Wang, et al. 116:1535 doi:10.1172/JCI25442 [Go to this article.]

Figure 6
β-catenin expression in epimorphin^–/– and WT mouse intestine. Nuclear protein isolation was performed as described in Methods. (A) Representative immunoblots of intestinal nuclear protein from WT, epimorphin^–/–, and epimorphin^+/– (HET) mice. Nuclear proteins (20 μg per lane) were electrophoresed, and immunoblots were incubated with an anti–β-catenin antibody. Blots were sequentially probed with an anti-lamin B1 antibody to control for differences in loading. (B) Quantification of nuclear β-catenin expression normalized to lamin B1 expression.