Epimorphin^–/– mice have increased intestinal growth, decreased susceptibility to dextran sodium sulfate colitis, and impaired spermatogenesis
J. Clin. Invest. Yuan Wang, et al. 116:1535 doi:10.1172/JCI25442 [Go to this article.]

Figure 4
Quantitative morphometric analysis of the small intestines of 3-week-old WT and epimorphin^–/– mice. (A) Villus heights, (B) crypt depths, (C) crypt cell proliferation, i.e., 5-BrdU incorporation, and (D) crypt fission in proximal jejunum from WT and epimorphin^–/– mice were measured as described in Methods. Data are expressed as mean ± SEM. WT, n = 14; KO, n = 16. *P < 0.05; **P < 0.02.