Anaphylactic shock depends on PI3K and eNOS-derived NO
J. Clin. Invest. Anje Cauwels, et al. 116:2244 doi:10.1172/JCI25426 [Go to this article.]

Figure 2
MAP measurements during PAF shock. C57BL/6 mice were challenged i.v. with 55 μg PAF at t = 0. (A) Individual MAP of PAF-challenged mice. (B) Individual MAP of mice treated with l-NAME (100 mg/kg, i.v., –2 hours) and PAF. (C) Data points show the mean MAP ± SD of the plots shown in A and B. Error bars are plotted as vertical lines above and below the curves. The number of mice is indicated between brackets. ***P < 0.0001.