Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
J. Clin. Invest. YuZhen Zhang, et al. 115:2870 doi:10.1172/JCI25327 [Go to this article.]

Figure 2
Macrophage RCT in SR-BI–knockout mice. SR-BI^–/– mice and wild-type littermates were injected intraperitoneally with [³H]cholesterol-labeled J774 foam cells in 2 independent experiments and results pooled for analysis (n = 11 per group). (A) [³H]cholesterol in plasma, liver, and feces. (B) Cholesterol mass and [³H]cholesterol lipoprotein profile of pooled plasma samples drawn 24 hours after injection of J774 cells subjected to FPLC analysis. *P < 0.05; **P < 0.01.