In humans, early cortisol biosynthesis provides a mechanism to safeguard female sexual development
J. Clin. Invest. Masahiro Goto, et al. 116:953 doi:10.1172/JCI25091 [
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Figure 2Growth and vascular development of the human early fetal adrenal gland. (
A) Relative proportion of adrenal gland (ADR) to kidney (KID) during early development. (
B) Weight (α SEM) of individual adrenal glands and developmental age. (
C and
D) Brightfield IHC with anti-CD34 to demonstrate vascular development counterstained by toluidine blue at 41 (
C) and 50 (
D) dpc. An adjacent H&E section is shown at the left of
C. ac, adrenal cortex; ao, aorta; c, capsule; mg, mesonephric glomerulus. Scale bars: 1 mm (
A), 300 μm (
C and D).
