Noninvasive imaging of pancreatic inflammation and its reversal
in type 1 diabetes
J. Clin. Invest. Stuart E. Turvey, et al. 115:2454 doi:10.1172/JCI25048 [
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Figure 2Tracking pancreatic inflammation during the development of autoimmune diabetes. Young female BDC2.5/NOD mice were injected with CPA to provoke autoimmune diabetes and were imaged at the indicated time points. Each group contained 4–7 mice. T2 values for pancreas (
A) and paraspinal muscles (
B) are shown. VVF (
C and
D) and microvascular leak (
E and
F) were estimated for each organ using formulae described in Methods. **
P < 0.01.