Tonsillar homing of Epstein-Barr
virus–specific CD8+ T cells and the
virus-host balance
J. Clin. Invest. Andrew D. Hislop, et al. 115:2546 doi:10.1172/JCI24810 [
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Figure 1EBV genome load quantitation in IM patients, post-IM patients, and long-term carriers. (
A) EBV genome copies in 1 ml of concentrated throat washing (upper panel) and 10
6 PBMCs (lower panel) from an IM patient (IM-171) from whom samples were taken during acute disease (days 0–14) and at intervals up to 4 months later. Upper limits of genome levels in throat washing and blood samples from healthy carriers are indicated by the dashed lines. (
B) EBV genome copies were estimated in 10
6 tonsillar cells (upper panels) or 10
6 PBMCs (lower panels) from tonsillectomy patients who were either undergoing acute IM or recently recovered from IM (post-IM) or were long-term carriers.