Vascular remodeling and the kallikrein-kinin system
J. Clin. Invest. Oscar A. Carretero, et al. 115:588 doi:10.1172/JCI24567 [
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Figure 2Arterial remodeling. (
A) Diagram showing the manner in which remodeling can modify the cross-sectional area of arteries. The vessel in the center represents a normal artery. Remodeling can be hypotrophic, represented by reduced cross-sectional area of the vessel wall (left); eutrophic, with no change in cross-sectional area (center); or hypertrophic, characterized by increased cross-sectional area (right). These forms of remodeling can be inward, showing decreased lumen diameter (top); or outward, with increased lumen diameter (bottom). Modified with permission from
Hypertension (
13). (
B) Diagram of a normal arterial wall (left) and an arterial wall with eutrophic inward remodeling, showing the decrease in both lumen and external diameter of the artery with normal wall area (right).