Ets-1 is a critical regulator of
Ang II-mediated vascular
inflammation and remodeling
J. Clin. Invest. Yumei Zhan, et al. 115:2508 doi:10.1172/JCI24403 [
Go to this article.]
Figure 4Immunohistochemical staining of PAI-1, p21
CIP, VCAM-1, and MCP-1 in the thoracic aorta of
Ets1+/+ and
Ets1–/– mice after Ang II infusion. Evaluation of expressions of PAI-1, cyclin-dependent kinase inhibitor p21
CIP, VCAM-1, and MCP-1 after 1 week of Ang II infusion (1.4 mg/kg/d) in the thoracic aorta of
Ets1+/+ compared with
Ets1–/– mice. Isotype-matched controls are shown below each panel. Original magnification, ×100; enlarged regions, ×400.
