Carcinoembryonic antigen–related cell adhesion molecule 1 modulates vascular remodeling in vitro and in vivo
J. Clin. Invest. Andrea Kristina Horst, et al. 116:1596 doi:10.1172/JCI24340 [
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Figure 4Destabilization of endothelial cell networks by anti-CEACAM1 antibodies. Anti-CEACAM1 antibody AgB10 (0.7 μM) was added to explants of
Ceacam1–/– mice, CEACAM1
endo+ mice, and their appropriate WT littermates for 6 days, and interference with endothelial tube formation is shown. Representative areas of the explants are marked with gray boxes and enlarged correspondingly on the right side of each panel. Magnification, ×100, ×200 (insets).
