In vivo expansion of CD4⁺CD45RO–CD25⁺ T cells expressing foxP3 in IL-2-treated HIV-infected patients
J. Clin. Invest. Irini Sereti, et al. 115:1839 doi:10.1172/JCI24307 [Go to this article.]

Figure 1
Expansion of naive CD4⁺CD25⁺ cells after IL-2 administration. (A) Representative example of phenotypic changes occurring after IL-2 administration. Dot plots of CD45RO and CD25 expression on CD4⁺ T cells of an HIV patient at baseline and after 3 cycles of IL-2. CD25-expressing CD45RO^– and CD45RO⁺ cells increased after IL-2 without significant change in the CD4⁺CD45RO⁺CD25^+high subset. (B) An example of the bead separation of studied CD45RO^– subsets is shown. Naive cells were defined as CD45RO^– and CD27⁺.