Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome
J. Clin. Invest. John A. Belperio, et al. 115:1150 doi:10.1172/JCI24233 [
Go to this article.]

Figure 5ELR
+ CXC chemokines are elevated during the pathogenesis of murine BOS. Real-time quantitative PCR of CXCL1 (
A) and CXCL2/3 (
B) mRNA expression presented as fold increase in chemokine expression in allografts compared with syngeneic controls at days 3, 7, 14, 21, and 28. Protein levels of CXCL1 (
C) and CXCL2/3 (
D) in allografts and syngeneic controls at days 3 through 28. (
E) FACS analysis of neutrophils from tracheal allografts undergoing BOS as compared with syngeneic controls. *P < 0.05.