Genetic and functional characterization of human pemphigus vulgaris monoclonal autoantibodies isolated by phage display
J. Clin. Invest. Aimee S. Payne, et al. 115:888 doi:10.1172/JCI24185 [
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Figure 3Characterization of scFv mAb desmoglein-binding specificity by ELISA. (
A) Patterns of the binding of selected scFv mAb clones to Dsg1 and Dsg3. (D3)3c/9 was isolated from a library panned on Dsg3 but showed quantifiable specificity for Dsg1, as shown in
B. Similar results were obtained for mAb (D3)3a/9 (data not shown).