Heme-regulated eIF2α kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and β-thalassemia
J. Clin. Invest. An-Ping Han, et al. 115:1562 doi:10.1172/JCI24141 [Go to this article.]

Figure 4
Severe anemia of Hri^–/–Hbb^–/– embryos during definitive erythropoiesis. (A) E17.5 embryos with different β–major genotypes. (B) Wright-Giemsa stained embryonic blood smears of E13.5 and E14.5. Original magnification, ×1,000. (C) Wright-Giemsa stained embryonic blood smears of E15.5 and E17.5. Original magnification, ×1,000.