Heme-regulated eIF2α kinase modifies the phenotypic severity of murine models of erythropoietic protoporphyria and β-thalassemia
J. Clin. Invest. An-Ping Han, et al. 115:1562 doi:10.1172/JCI24141 [Go to this article.]

Figure 2
Inclusions in Hri^–/–Fech^m1Pas/m1Pas rbcs are composed of both α- and β-globins. The globin chain compositions in the soluble hemoglobin (sup) and the aggregated inclusions (pellet) were analyzed by HPLC. β-maj, β-major; β-min, β-minor.