Inhibition of TNF receptor 1 internalization by adenovirus 14.7K as a novel immune escape mechanism
J. Clin. Invest. Wulf Schneider-Brachert, et al. 116:2901 doi:10.1172/JCI23771 [Go to this article.]

Figure 1
14.7K protects NIH 3T3 cells from TNF-induced apoptosis. NIH 3T3 and C127 cells expressing either PM-14.7K (A and C) or 14.7K (B and D) were treated with 100 ng/ml TNF for 18 hours in the absence (b lines) or presence of 12.5 μg/ml CHX (dotted lines). TNF-induced apoptosis was monitored by FITC–annexin V staining using FACS analysis.