TWEAK induces liver progenitor
cell proliferation
J. Clin. Invest. Aniela Jakubowski, et al. 115:2330 doi:10.1172/JCI23486 [
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Figure 6Fn14 and TWEAK are upregulated in the reactive portal area (including oval cells and bile ducts) in the DDC-fed mice but not in control mice fed regular diet with no DDC. Fn14 expression was detected by in situ hybridization. Dark- and brightfield pictures of the same field are displayed in (
A) a control mouse on regular diet and (
B) a DDC-fed mice on day 7. TWEAK expression in (
C) control mouse on regular diet and (
D) DDC-fed mouse on day 7. Magnification, ×250.
