Pemphigus foliaceus IgG causes dissociation of desmoglein 1–containing junctions without blocking desmoglein 1 transinteraction
J. Clin. Invest. Jens Waschke, et al. 115:3157 doi:10.1172/JCI23475 [Go to this article.]

Figure 5
Characterization of cell-to-bead contacts induced by Dsg1-coated beads. Scanning electron microscopy (A) and transmission electron microscopy (B) were used to characterize contacts between HaCaT cells and Dsg1-coated beads formed after 30 minutes of settlement. Finger-like processes were present underneath beads with direct contact to HaCaT cells (arrows). These processes were similar to the desmosome-bearing processes found at contact sites between neighboring cells (arrowhead). Scale bars: 2.5 μm (A), 1.25 μm (A, inset); 1.0 μm (B).