Reflecting on 80 years of excellence
J. Clin. Invest. Ushma Savla, et al. 114:1006 doi:10.1172/JCI23290 [Go to this article.]

Figure 6
Advertisements for the antileukemic drug Purinethol in 1954 (A) and 1963 (B). The later ad reflects the Harris-Kefauver Amendment to the Food, Drug and Cosmetic Act in 1962, which established requirements for disclosure of drug mechanisms and side effects.