AMP-activated protein kinase: the guardian of cardiac energy status
J. Clin. Invest. D. Grahame Hardie, et al. 114:465 doi:10.1172/JCI22683 [Go to this article.]

Figure 2
Role of AMPK in regulating energy balance at the whole-body level. Green arrows indicate positive effects, and red lines with bars indicate negative effects. In the hypothalamus, activation of AMPK in response to low glucose or leptin levels increases food intake (18, 19); references for other effects of AMPK activation can be found in recent reviews (1). FA, fatty acid.