MyD88-dependent induction of allergic Th2 responses to intranasal antigen
J. Clin. Invest. Damani A. Piggott, et al. 115:459 doi:10.1172/JCI22462 [
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Figure 4Pulmonary DCs are not activated by LPS in the absence of MyD88 in vivo. (
A) MHC class II and CD86 FACS analysis, at 48 hours, of CD11c
+ lung cells from WT and MyD88-deficient mice sensitized to OVA/LPS or PBS intranasally. (
B) MHC class II and CD86 FACS analysis of CD11c
+ BMDCs generated from WT and MyD88-deficient mice pulsed with OVA/LPS overnight or left untreated (no Tx).