PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells
J. Clin. Invest. Naoko Hashimoto, et al. 115:138 doi:10.1172/JCI22232 [
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Figure 6Altered gene expression in the islets of βPKCλ
–/– mice. The abundance of mRNAs for the indicated proteins was determined by real-time RT-PCR analysis of total RNA isolated from islets of control and βPKCλ
–/– mice. The amounts of the mRNAs in βPKCλ
–/– mice are expressed relative to those in control animals. Data are means ± SE of triplicates for pooled total RNA samples from 6 mice of each genotype and are representative of a total of 3 similar experiments. *
P < 0.05 (ANOVA) versus the corresponding value (1.0) for control mice.
