PKCλ regulates glucose-induced insulin secretion through modulation of gene expression in pancreatic β cells
J. Clin. Invest. Naoko Hashimoto, et al. 115:138 doi:10.1172/JCI22232 [Go to this article.]

Figure 3
Impairment of glucose-stimulated insulin secretion in isolated islets of βPKCλ^–/– mice. Insulin release in response to the indicated concentrations of glucose (A), KCl (B), or tolbutamide (C) was measured with islets isolated from control (white bars) or βPKCλ^–/– (black bars) mice. Data are means ± SE of values from 6 animals of each genotype. *P < 0.05 (ANOVA) versus the corresponding value for control mice.