Impairment of tubuloglomerular feedback regulation of GFR in ecto-5′-nucleotidase/CD73–deficient mice
J. Clin. Invest. Hayo Castrop, et al. 114:634 doi:10.1172/JCI21851 [
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Figure 3Change of heart rate in response to 5′-AMP. (
A) Heart rate in
e-5′
NT/CD73+/+,
e-5′
NT/CD73–/–, and
A1AR–/– mice during control and during the injection of 5, 10, 20, and 30 μg of 5′-AMP. (
B) Decrease of heart rate compared with control; significance is given for the comparison between
e-5′
NT/CD73+/+ and
e-5′
NT/CD73–/– mice.
