The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity
J. Clin. Invest. David G. Bowen, et al. 114:701 doi:10.1172/JCI21593 [Go to this article.]

Figure 4
Hepatitis did not occur in Alb-K^b mice on the same genetic background as Met-K^b mice following adoptive transfer of Des-TCR LN cells, despite similar levels of antigen expression by hepatocytes. (A) Serum ALT levels of H-2^dk recipient Met-K^b, Alb-K^b, and control mice following adoptive transfer of Des-TCR (H-2^dk) LN cells. Data points represent means ± SEM for groups of 4 mice. (B) H-2K^b expression by viable (PI^– ) hepatocytes from H-2^dk Alb-K^b, Met-K^b, and control mice, analyzed by flow cytometry.