Cortical spreading depression activates and upregulates MMP-9
J. Clin. Invest. Yasemin Gursoy-Ozdemir, et al. 113:1447 doi:10.1172/JCI21227 [Go to this article.]

Figure 2
CSD upregulated MMP-9 mRNA in piriform cortex at 1, 3, and 6 hours. The housekeeping gene GAPDH is shown for comparison. MMP-9 mRNA was constitutively expressed in both brain cortices from control and contralateral to CSD.