Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia
J. Clin. Invest. Pranavkumar Shivakumar, et al. 114:322 doi:10.1172/JCI21153 [Go to this article.]

Figure 8
Hepatic population of T lymphocytes and cytokine expression in IFN-γ^–/– mice. Flow cytometry shows a decreased population in the livers of IFN-γ^–/– mice by CD3⁺CD4⁺ and CD3⁺CD8⁺ lymphocytes after RRV challenge (A–C). Despite the loss of IFN-γ, expression of hepatic mRNA expression for IL-2p40, IL-4, and IL-5 in response to RRV challenge does not change (D–F). n = 4–7 mice per group at each time point. *P < 0.04.