Hepatitis C virus mutation affects proteasomal epitope processing
J. Clin. Invest. Ulrike Seifert, et al. 114:250 doi:10.1172/JCI20985 [
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Figure 1Prevalence of synonymous (open circles) and nonsynonymous (filled circles) HCV mutations within the HCV NS3
987–1133 sequence isolated from HLA-A2 positive, persistently infected HCV patients 18 years after a single-source outbreak of hepatitis C. The arrow indicates the amino acid position with the highest rate of nonsynonymous to synonymous mutations.