Hypoxia induces a functionally
significant and translationally efficient neuronal NO synthase mRNA variant
J. Clin. Invest. Michael E. Ward, et al. 115:3128 doi:10.1172/JCI20806 [
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Figure 6Effect of hypoxia on nNOS promoter/
LacZ reporter transgenic mice. (
A) General schema of the insertional exon 2 nNOS promoter/
LacZ reporter transgene construct used to generate the transgenic mouse line. Representative histological sections are shown for β-galactosidase expression in renal papilla (Magnification: ×200) and brain (Magnification: ×250) from nNOS/
LacZ (
B) and eNOS/
LacZ reporter (
C) mice exposed to normoxia or hypoxia; indicated magnifications are approximate.