Hypoxia induces a functionally significant and translationally efficient neuronal NO synthase mRNA variant
J. Clin. Invest. Michael E. Ward, et al. 115:3128 doi:10.1172/JCI20806 [Go to this article.]

Figure 1
Concentration-response relationships for PE-induced contraction in the presence and absence of L-NAME (10 μM) for endothelium-intact and -denuded aortic rings from normoxic rats (A) and rats exposed to hypoxia for 48 hours (B) (n = 7 per group). *P < 0.05 for differences between untreated rings from normoxic and hypoxia-exposed rats. ^‡P < 0.05 for differences between L-NAME–treated and –untreated rings from hypoxia-exposed animals (ANOVA).